What is the EVA trial?
EVA stands for the Elective Vitrification of All embryos. This is a ground breaking trial that Genea is performing. In this trial, some patients will have their first (best) embryo transferred fresh and a second group will have all embryos frozen, with the first best embryo transferred one month later in the woman’s natural ovulation cycle.
Why is Genea undertaking this trial?
Genea’s pregnancy rates now show no difference between fresh embryo transfers and frozen-thawed embryo transfers. This is because the latest method of embryo freezing (vitrification) do not appear to harm the embryo or lower the chance of implanting.It is now also apparent that the high hormone environment in fresh cycles might abnormally alter the uterine lining. This means that transferring the best embryo fresh might actually lead to a lower chance of success to transferring the best embryo frozen-thawed, one month later.
Who can take part in the trial?
Couples having their first or second fresh cycle of IVF, where the woman is less than 38 years old. Remember you would need to have the trial fully discussed with you by your Genea specialist and you need to give written consent before participating. Like all trials, participation is voluntary.
Can I choose which part of the trial I will be in?
No – this is a randomised trial, where patients are randomly allocated to either group.
If I am in the “freeze all” group, won’t my chance be lower?
No, as discussed above. At the very least it would seem to be no different and might actually be better.
Will freezing all embryos involve more cost?
No, for patients in the trial the costs will be the same no matter which part of the trial you are in.
This is for general information only. There is a formal information sheet and consent forms that must be read and completed in conjunction with a detailed discussion with your Genea specialist.