PGD-CGH possible outcomes
Not all embryos may be suitable for biopsy. They may however, be suitable for freezing or transfer.
An answer is achieved from over 94% of all embryos tested. For technical reasons, we may not get an answer on an individual embryo and the genetic status of that embryo will be unknown. These embryos may still be suitable for clinical use.
No embryos with desired genetics
Embryos tested and deemed abnormal or affected are unsuitable for transfer.
The amplification of a few copies of DNA (extracted from a few cells biopsied from an embryo) into millions of copies is at risk of contamination from extraneous human DNA. While we take stringent precautions against contamination, there is always a small risk of contamination resulting in a misdiagnosis.
Not all cells in an embryo may contain the same number of chromosome. PGD cannot look at every cell in an embryo and the biopsy piece may not represent the whole embryo. CGH can not detect low level mosaicism.
For the above reasons, the accuracy of the test is offered at 95%.