What does PGD / PGS involve?

Genea's Pre-implantation Genetic Diagnosis scientists have helped hundreds of families achieve their dream of taking home a healthy baby. We first launched chromosome testing of embryos in 1995 with gene testing introduced in 1998. Since then our PGD techniques have led the world.

Genea is one of the very few centres in Australia with the vital combination of IVF and genetics facilities to perform these sophisticated tests successfully. Genea was the first clinic in the world to perform blastocyst stage biopsy and we introduced it as routine in our labs in 2004. A review of information captured by the Australian and New Zealand Assisted Reproduction Database (ANZARD) between 2004 and 2008 showed our Day 5/6 biopsy approach to PGD resulted in a significant lift in IVF success rates and the number of babies born.

The data review showed blastocyst biopsy for PGD improves both implantation and live birth rates when compared to biopsy at Day 3. Since then, blastocyst stage biopsy has become a world standard - an innovation led by the Genea team. Learn more about Genea's PGD success rates

Understanding PGS and PGD

PGS chromosome testing can help in cases of advanced maternal age, multiple miscarriages and failed embryo transfers.

Humans generally have 46 chromosomes that come as 23 pairs, one of each pair from our Mum and one of each from our Dad. Problems arise when an embryo randomly misses out on a chromosome or picks up an extra one – that’s called a chromosomal abnormality.

Chromosomal abnormalities can cause your embryo to fail to implant or miscarry or they might result in a baby born with developmental problems or a serious genetic condition.

Chromosomes in detail
Background to PGD and PGS

Genetic tests

At Genea our scientific team use two major types of tests or analysis:

1. Total Chromosome Analysis
2. Polymerase Chain Reaction (PCR)
Combination Polymerase Chain Reaction (Chromosome Analysis / PCR)

Further information

Embryo Biopsy
Analysis
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