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23 September 2025: ADHD, Autism & Paracetamol in Pregnancy: What the science shows

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Donald Trump's claim that pregnant women should avoid paracetamol due to an unproven link to autism has sparked concern and confusion in Australia. Medical experts here are urging calm, emphasising that the claim is not supported by conclusive evidence.

The Australian Medical Association has stated clearly that no studies demonstrate paracetamol use in pregnancy causes autism. While some observational studies have identified an association, others have found no link at all, and experts are consistent in noting that association does not equal cause. Autism is most likely driven by genetic factors, though the full picture remains unclear.

Associate Professor Alex Polyakov, Medical Director at Genea Fertility Melbourne, has weighed in on the research underpinning Trump's claim, explaining that the US review in question does not present new findings but rather synthesises existing evidence, most of which is retrospective in design. Retrospective studies can identify associations but cannot establish cause and effect. He notes, for example, that fever itself during pregnancy may be a contributing factor to developmental outcomes, making it difficult to isolate the role of paracetamol.

Assoc Prof Polyakov's advice for pregnant women is measured: the balance of evidence suggests that prolonged or high-dose paracetamol use may carry risks, while occasional short-term use is unlikely to be harmful. As with all medications during pregnancy, the lowest effective dose for the shortest possible time is recommended, and any persistent symptoms should be discussed with a healthcare provider.

Read the full article for a detailed breakdown of the research and expert commentary.

Read the full online article here

A/Prof Alex Polyakov

Associate Professor Alex Polyakov is an Obstetrician, Gynaecologist and Fertility specialist practicing in East Melbourne. A/Prof Polyakov is unique among fertility specialists by offering a holistic approach that encompasses surgical, fertility, and obstetric care. This means Alex is highly trained to perform surgical interventions for gynaecological conditions such as fibroids, endometriosis, and intrauterine polyps/adhesions. 

Learn more

AProf Alex Polyakov news article
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